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Mendelson's syndrome is characterised by a bronchopulmonary reaction following aspiration of gastric contents during general anaesthesia due to abolition of the laryngeal reflexes. The main clinical features are signs of general hypoxia, two to five hours after anaesthesia.
Learn about Mendelson syndrome, a respiratory disorder caused by the aspiration of gastric contents into the lungs. Explore its causes, symptoms, diagnosis, treatment options, and management strategies to minimize complications and improve outcomes.
Jun 12, 2023 · “Mendelson syndrome” was initially described as aspiration of gastric contents causing a chemical pneumonitis characterized by fever, cyanosis, hypoxia, pulmonary edema, and potential death. Among the patients studied, there were 66 cases of aspiration (0.15%) and two deaths (0.0045%).
- Irim Salik, Tara M. Doherty
- 2023/06/12
- Clinical Presentation
- Pathology
- Radiographic Features
- History and Etymology
- Differential Diagnosis
This syndrome develops rapidly (2-12 hours after aspiration) and within hours the patient may become 1. tachypneic 2. hypoxic 3. febrile Other signs include 1. bronchospasmwith need for increasing ventilation pressure 2. bronchial hypersecretion 3. pulmonary vasoconstriction 4. cyanosis Usually there is minimal sputum production ref.
The primary pathogenesis is secondary to the aspiration of acidic stomach contents, although other body juices, e.g. bile, may also play a role. The chemical burns and causes occlusion of bronchi and bronchioles damaging the epithelium typically leading to pulmonary edema (ARDS). Secondary bacterial superinfection (aspiration pneumonia)may develop.
Plain radiography and CT may depict fleeting infiltrates (which do not last more than one to two days), atelectasisand non-cardiac lung edema.
It is named after the American obstetrician and cardiologist (dual certified) Curtis L Mendelson (1913-2002), who described it in 1946 2.
in chronic state may mimic a lung massJan 1, 2018 · Mendelson's syndrome is an acute pneumonia caused by regurgitation of stomach contents and aspiration of chemical material, usually gastric juices. The pneumonia develops rapidly, and within hours the patient may become tachypnoeic, hypoxic and febrile.
Jun 12, 2023 · “Mendelson syndrome” was initially described as aspiration of gastric contents causing a chemical pneumonitis characterized by fever, cyanosis, hypoxia, pulmonary edema, and potential death. Among the patients studied, there were 66 cases of aspiration (0.15%) and two deaths (0.0045%).
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