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  1. De Soto is a city in Jefferson County, Missouri, United States. The population was 6,449 at the 2020 census and the city is part of the St. Louis metropolitan area. The Van Metre family were first to settle in 1803.

  2. This is a list of sites and peoples visited by the Hernando de Soto Expedition in the years 1539–1543. In May 1539, de Soto left Havana, Cuba, with nine ships, over 620 men and 220 surviving horses and landed at Charlotte Harbor, Florida.

  3. Sep 26, 2023 · Situated about 45 miles south of St. Louis, De Soto has a rich historical background and offers a delightful mix of small-town charm with modern amenities. Let's delve into the captivating history and interesting facts about this delightful city.

  4. Dec 28, 2020 · Things to Do in De Soto, Missouri: See Tripadvisor's 539 traveler reviews and photos of De Soto tourist attractions. Find what to do today, this weekend, or in October. We have reviews of the best places to see in De Soto. Visit top-rated & must-see attractions.

  5. The City of De Soto is located in the southeastern part of Missouri, approximately 45 miles south of St. Louis. De Soto is in Jefferson County, which is one of the fastest growing counties in Missouri.

  6. De Soto (1500–1542) was the first European to document the river. The image shows him and his men approaching the river and a group of Native Americans camped there. At the center, de Soto, riding a white horse, moves toward the American Indians, who watch in front of their tepees. A chief holds out a peace pipe to de Soto.

  7. move to sidebarhide. From Simple English Wikipedia, the free encyclopedia. De Sotois a city in Jefferson County, Missouri, United States. v. t. e. Municipalities and communities of Jefferson County, Missouri, United States. County seat: Hillsboro.

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