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      • Any dog can potentially develop primary lens luxation as a secondary complication of other eye problems like glaucoma or cataracts, but the primary means of transmission of the condition is by heredity, and dogs that are themselves affected by the hereditary form of the condition (rather than developing it due to another issue) run the risk of passing the condition on to their own offspring.
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  2. Mar 21, 2022 · Symptoms and diagnosis. Primary lens luxation in dogs can be hard to spot until it becomes quite pronounced, as the condition tends to develop quickly after it begins. Initially, the eye in question may appear to be a little red and inflamed, and your dog may show signs that it is bothering them.

  3. If a dog is homozygous for the mutation, it is highly likely to develop lens luxation in its lifetime. Regular ophthalmic examinations (every six to 12 months) from the age of 18 months are recommended so treatment can be instigated as soon as possible.

  4. What causes lens luxation? In some dogs, particularly the terrier breeds, the support ligaments of the lens weaken or break, causing the lens to dislocate from its normal position. It can fall backwards into the eye (known as a posterior luxation) where it rarely causes discomfort.

  5. A variant in the ADAMTS17 gene causes primary lens luxation (PLL). It is inherited in a codominant or additive fashion, meaning dogs with two copies of the variant are at the highest risk of developing the disease. Testing for this gene can help breeders select appropriate mating pairs.

  6. Mar 21, 2022 · Any dog can potentially develop primary lens luxation as a secondary complication of other eye problems like glaucoma or cataracts, but the primary means of transmission of the condition is by heredity, and dogs that are themselves affected by the hereditary form of the condition (rather than developing it due to another issue) run the risk of ...

  7. If the lens falls into the anterior chamber of the eye, glaucoma and loss of vision can quickly result. PLL is a well-recognised, painful and blinding inherited eye condition that affects many breeds of dog.

  8. There are both primary and secondary causes that are indicative of the origin of lens luxation. The primary cause of lens luxation is heredity, causing the degeneration of the suspensory or zonular fibers. This occurs mostly in Terrier dogs such as: Tibetan Terrier; Wire Haired Fox Terrier; Smooth Haired Fox Terrier; Scottish Terrier; Welsh Terrier

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