Search results
Jul 17, 2024 · Shiga toxins (Stx1, Stx2) enzymatically inactivate the eukaryotic ribosome by removal of a single nucleobase (adenine) from 28 s rRNA within the large ribosomal subunit (60S). This single-base modification triggers an irreversible process that inhibits the interaction between the ribosome and the eucaryotic elongation factors, preventing the binding of the aminoacyl-tRNA (Chan and Ng 2016 ).
5 days ago · The main STEC virulence factors are Shiga toxins, encoded by stx1 and stx2 genes carried by bacteriophages. Stx is an AB5 toxin that damages the microvascular endothelial cells of the kidney, gut and brain in humans . Both Shiga toxin genes present a number of variants.
4 days ago · The unnamed toxins are powerful indeed, causing, we are told, ailments ranging from asthma, allergies and prostate problems to cancer, heart disease and an impaired sex drive. But luckily there is salvation in sight.
5 days ago · Here, we discover an orphan antitoxin counter-defense element in T4-like phages that can overcome the bacterial toxin-antitoxin phage defense system, DarTG1. The DarT1 toxin, an ADP-ribosyltransferase, modifies phage DNA to prevent replication while its cognate antitoxin, DarG1, is an ADP-ribosylglycohydrolase that reverses these modifications ...
4 days ago · Embark on a nature-lovers experience starring regional cuisine in the picturesque Shiga Prefecture! Discover a charming mountain village, engage with local artisans, enjoy a Japanese lunch using regional ingredients, embark on a nature hike, and more.
4 days ago · Aim of method: Detection of Shiga-toxin producing E. coli. Holder: OXOID Thermo Fisher. Certificat / Summarized study report. BAX® System Real-Time PCR Assays for STEC Suite and BAX® System Real-Time PCR Assays for E. coli O157:H7.
3 days ago · Discover the best restaurants near Naoya Shiga house, Kinki Area - Nara, Mie, Wakayama. Find available tables for your party size and preferred time and book your perfect spot.
