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3 days ago · Familial Mediterranean fever (FMF) is a monogenic recessive autoinflammatory disease due to biallelic mutations in MEFV and characterized by recurrent attacks of fever and abdominal pain . Early initiation of lifelong colchicine treatment has changed the natural history of the disease and patients now have a near normal lifespan [2] .
3 days ago · • Italian children with familial Mediterranean fever tend to have an early age of onset, primarily manifesting with recurrent fever and characteristic associated symptoms. • Many MEFV gene variants are present in Italian children with familial Mediterranean fever, and these patients are most often heterozygous, exhibiting a mild to moderate phenotype.
Oct 19, 2024 · Familial Mediterranean fever (FMF) is characterized by recurrent episode of fever, serositis, oligoarticular arthritis, and rash, beginning between the ages of 5 and 15 years and tending to occur every 2 to 4 weeks.
3 days ago · « Familial mediterranean fever is associated with increased risk for ischaemic heart disease and mortality–perspective derived from a large database »
Oct 4, 2024 · Symptoms such as sweats, weight loss, and itching (these suggest a hematologic malignancy). Immunosuppression (transplant patient, previous autoimmune disease, HIV). Lumps. Familial disorders (e.g., familial Mediterranean fever). Every symptom should be explored in detail.
Oct 19, 2024 · Abdominal pain was the most common symptom (90.3%), followed by fever (69.0%) and arthralgia (42.3%). Consanguinity was reported in 35.1% of cases, mainly between first-degree cousins, and 24.5% had a family history of FMF.
3 days ago · Illnesses and conditions. Infections and poisoning. Fever in adults. A fever is usually when your body temperature is 38°C or higher. You may feel warm, cold or shivery. You can find out if you have a fever (high temperature) by using a thermometer to take your temperature.
