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  1. 2 days ago · The production was part of the Almeida’s season at the Albery Theatre (now the Noël Coward Theatre) and was directed by Jonathan Kent. Hedda Gabler Ibsen’s icy, frustrated anti-heroine was a perfect role for the razor-sharp Blanchett, in an edgy production directed by her husband Andrew Upton.

  2. 1 day ago · Snowpiercer (TV series) Snowpiercer is an American post-apocalyptic dystopian thriller television series that premiered on May 17, 2020, on TNT. It is based on both the 2013 film of the same name, directed by Bong Joon-ho, and the 1982 French graphic novel Le Transperceneige by Jacques Lob, Benjamin Legrand and Jean-Marc Rochette, from which ...

  3. 3 days ago · [The Blacks: A Clown Show (French: Les Nègres, clownerie; published in 1958, premièred in Paris in 1959) by Jean Genet ran at the St. Mark's Playhouse in Manhattan’s East Village from 4 May 1961 to 27 September 1964 (1408 performances). The New York première was produced by Sidney Bernstein, George P. Edgar, and Andre Gregory, and directed by Gene Frankel from Bernard Frechtman’s ...

  4. 1 day ago · A 26-year-old man with Ehlers-Danlos syndrome, recurrent otitis externa, and chronic otitis media sustained a left lower extremity amputation and open femur fracture with internal hardware fixation after a motor vehicle collision in Arizona. He presented to the emergency department at our institution with severe left leg pain and purulent discharge despite receiving two unidentified ...

  5. 3 days ago · Defining heritability, plasticity, and transition dynamics of cellular phenotypes in somatic evolution. Phylogenetic analysis of trait heritability (PATH) applies phylogenetic correlations to ...

  6. 3 days ago · B cells contribute to the pathogenesis of neuropathic pain, but the exact mechanisms remain elusive. Lacagnina et al. report increased immunoglobulin G (IgG) in the dorsal root ganglia (DRGs) of mice after peripheral nerve injury (PNI) and patients with chronic pain.

  7. 2 days ago · Examination of CSF proteins in mutation carriers and non-carriers for autosomal dominant Alzheimer’s disease uncovers early proteomic changes and generates a robust ADAD prediction model. The findings highlight the similarities and differences between ADAD and sporadic Alzheimer’s disease, which can lead to personalized medicine for mutation carriers in ADAD genes.