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  2. Although components of possible Parkinson's disease can be found in very early documents, the first clear medical description was written in 1817 by James Parkinson. In the mid-1800s, Jean-Martin Charcot was particularly influential in refining and expanding this early description and in disseminating information internationally about Parkinson ...

    • PubMed

      PubMed - The History of Parkinson's Disease: Early Clinical...

  3. The history of Parkinson's disease expands from 1817, when British apothecary James Parkinson published An Essay on the Shaking Palsy, to modern times. Before Parkinson's descriptions, others had already described features of the disease that would bear his name, while the 20th century greatly improved knowledge of the disease and its ...

  4. Although components of possible Parkinson's disease can be found in very early documents, the first clear medical description was written in 1817 by James Parkinson.

    • Christopher G. Goetz
    • 2011
  5. First described in 1817 by English physician James Parkinson as a "shaking palsy," Parkinson’s Disease (PD) is a progressive neurological disorder of the brain that results from a loss of cells that produce dopamine.

    • Why Is It called Parkinson’s Disease?
    • How Life with Parkinson’s Disease Once Was
    • The Evolution of Parkinson’s Disease Treatment
    • Where Do We Go from Here?
    • Talk with Others Who Understand

    The first time Parkinson’s disease was documented in writing was in 1817, when British physician James Parkinson penned an essay about a trembling paralysis that he called “the shaking palsy.” Parkinson was born north of London in 1755. After completing his medical education, he took over the medical practice of his father, who had died suddenly. I...

    In his essay, James Parkinson’s discussion of the nonmotor symptoms of Parkinson’s disease was somewhat ahead of its time. That is evident in the research that followed, which often left out symptoms considered to relate to a person’s quality of life. While physicians historically focused on treating visible motor issues, many people were on their ...

    During the early years of Parkinson’s disease treatment, the only medications used were antimuscarinic alkaloids derived from the belladonna plant. By blocking involuntary nerve impulses, these therapies reduced tremors and were quickly popularized for their ability to manage this symptom of Parkinson’s disease. In the 1940s and 1950s, synthetic ve...

    There’s no cure for Parkinson’s disease, but the outlook is getting brighter with each passing year. Medical advancements have led to earlier diagnosis, longer life spans, and treatment options beyond medication (such as deep brain stimulation). Cellular and genetic treatments have been discussed since the 1980sand are gradually gaining traction in...

    MyParkinsonsTeam is the social network for people with Parkinson’s disease and their loved ones. On MyParkinsonsTeam, more than 87,000 members come together to ask questions, give advice, and share their stories with others who understand life with Parkinson’s disease. Share your experience in the comments below, or start a conversation by posting ...

  6. In 1817, English physician James Parkinson published the first comprehensive medical description of the disease as a neurological syndrome in his monograph An Essay on the Shaking Palsy. [224] [225] He presented six clinical cases, including three he had observed afar near Hoxton Square in London. [226]

  7. Although components of possible Parkinson’s disease can be found in very early docu-ments, the first clear medical description was written in 1817 by James Parkinson.

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