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HIT delivers effective interventions on drugs, community safety and other public health concerns. We produce publications, run mass media campaigns, deliver training, organise conferences and provide consultancy to individuals, community groups, health and social care and criminal justice agencies locally, nationally and at an international level.
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Jan 8, 2015 · If clinical suspicion for HIT is at least moderate, all sources of heparin must be discontinued and treatment with a non-heparin anticoagulant considered. Heparin induced thrombocytopenia (HIT) is a clinicopathological syndrome that occurs when heparin dependent IgG antibodies bind to heparin/platelet factor 4 complexes to activate platelets ...
- Lori-Ann Linkins
- 2015
Heparin-induced thrombocytopenia ( HIT) is the development of thrombocytopenia (a low platelet count), due to the administration of various forms of heparin, an anticoagulant. HIT predisposes to thrombosis (the abnormal formation of blood clots inside a blood vessel ). When thrombosis is identified the condition is called heparin-induced ...
May 16, 2023 · Heparin-induced thrombocytopenia (HIT) is a severe complication that can occur in patients exposed to any form or amount of heparin products.[1] A fall in platelet counts and a hypercoagulable state characterize HIT. Patients who experience HIT may also develop thromboembolic complications that are associated with morbidity and mortality. This is a significant burden since heparin is widely ...
Oct 23, 2020 · Heparin-induced thrombocytopenia (HIT) is a prothromobotic adverse drug reaction occurring in <0.1% to 7% of patients receiving heparin products, depending on the patient population, type of heparin, and duration of exposure. 1-3 One-third to one-half of cases are complicated by thromboembolism, which may be limb- or life-threatening. 4-6
Oct 27, 2023 · Heparin-induced thrombocytopenia (HIT) is a life-threatening complication of exposure to heparin (ie, unfractionated heparin, low molecular weight [LMW] heparin) that occurs in up to 5 percent of patients exposed, regardless of the dose, schedule, or route of administration. HIT results from an autoantibody directed against platelet factor 4 ...
Aug 12, 2022 · Heparin-induced thrombocytopenia (HIT) is a potentially life-threatening complication of taking the drug heparin. Heparin is an anticoagulant (blood thinner) that prevents blood clots. A blood clot is a gel-like collection of blood in your veins or arteries.
