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  1. Guidelines. These guidelines are only guides to best practice which inevitably changes with passage of time. All practitioners need to undertake clinical care on an individualised basis and keep themselves up to date with changes in practice of clinical medicine.

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    • Is This Guideline Up to Date?
    • Guideline Development Process

    This guideline includes recommendations on: 1. indications for starting dialysis 2. planning and choosingtreatments 3. switching or stopping treatments 4. recognising symptoms 5. diet and fluids 6. information, education and support 7. coordinating care

    Healthcare professionals
    Providers of renal replacement therapy and conservative management
    People with chronic kidney disease stages 4 and 5, their families and carers

    August 2023: We have found no new evidence that affects the recommendations. For more information, see the surveillance decision.

    How we develop NICE guidelines This guideline updates and replaces NICE guideline CG125 (July 2011) and NICE technology appraisal guidance 48 (September 2002).

  2. Renal transplant recipients are at an increased risk of infection, cardiovascular disease, drug interactions, various degrees of renal impairment and transplant rejection. Early discussion with renal on-call will allow tailored advice and expedite investigation in case of potential rejection.

  3. In this guideline, we consider the randomised controlled trial lifestyle interventions as well as observational cohort study evidence in adult kidney +/- pancreas transplant recipients that can lead to improvement in cardiometabolic risk factors after transplantation.

  4. THE GUIDELINE. 3.1. Organ retrieval and transplantation surgery. 3.1.1. Living-donor nephrectomy. The endoscopic (laparoscopic) approach is the preferred technique for living-donor nephrectomy in established kidney transplant programmes [ 3 ].

  5. May 3, 2024 · Remote ischemic conditioning (RIC) has the potential to benefit graft function following kidney transplantation by reducing ischemia-reperfusion injury; however, the current clinical evidence is inconclusive.

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  7. Nov 2, 2020 · Remote ischaemic conditioning (RIC) is currently being explored as a non-invasive method to attenuate ischaemia/reperfusion injuries in organs. A randomised clinical study (CONTEXT) evaluated the effects of RIC compared to non-RIC controls in human kidney transplants. Methods.

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