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    • Describe Alpha Synuclein and The Role It Plays in Parkinson’s disease.
    • Why Is It Important to Diagnose Parkinson’s early?
    • How Will This Discovery Help Advance New Treatments?
    • What Does This Discovery Mean to The Parkinson’s Research Community?

    Abnormalities in alpha synuclein, a protein normally found in the nervous system, is associated with damage to neurons. Aggregates of misfolded and clumping of alpha synuclein that accumulate in the nervous system have been considered a hallmark of Parkinson’s disease (PD), but until now have only been detectable post-mortem. This new assay enables...

    To date, we have only been able to treat the symptoms of the disease. Since PD is a progressive, neurodegenerative disease, a major goal has been to develop an intervention that could slow, or even stop progression. The sooner in the disease course one could do that, the better off the patient would be. Of course, the “holy grail” would be to actua...

    This assay will enable us to establish objective endpoints for clinical trials of PD treatments, ensure study participants exhibit appropriate pathology, and detect therapy induced changes in their status. All of these factors will significantly decrease the risk to industry to invest in the development of potential “blockbuster” therapies, includi...

    I have spent my entire academic career at the University of Rochester and have focused on PD, both clinical care of patients and clinical research. To witness the growth and be part of this worldwide effort has been inspiring and I am thrilled with this breakthrough. There is a unique sense of energy and commitment that comes from being part of som...

  2. Dr. Christine Stewart, MD. Discover 1,624 Primary Care Doctors in Rochester, NY. 32% have 4 star+ reviews. View profiles with hours and locations, patient reviews, hospital affiliations, and...

  3. Michael F Evans Age: 75. Remove My Record. ... 153 Pinebrook Dr Rochester, NY 14616 1663. Monroe County Last reported in January of 1. Current Address Property Summary.

  4. Michael is an assistant professor of Pediatric Infectious Diseases at University of Rochester Medical Center (URMC). Michael earned his B.S. and M.S. degrees in biological sciences from Duquesne University in Pittsburgh, PA.

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