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This article aims to summarize the most recent knowledge of non-erosive reflux disease and reflux hypersensitivity to discuss the utility of Rome IV criteria in the identification and management of functional esophageal disorders.
Jun 16, 2023 · Gastro-oesophageal reflux disease (GORD) is a clinical diagnosis. The classic symptoms are heartburn and regurgitation. A therapeutic trial of a proton-pump inhibitor (PPI) can serve for both diagnosis and initial treatment. Upper endoscopy is indicated to evaluate for complications; for atypical...
Mar 20, 2023 · This topic review will review the clinical manifestations, diagnosis, and management of non-acid reflux. A general approach to patients with suspected GERD who have persistent symptoms despite PPI therapy is presented separately.
Feb 1, 2013 · Non-erosive reflux disease (NERD) and functional heartburn (FH) are two different clinical entities and the clear distinction between the two forms is actually possible thanks to the use of impedance-pH monitoring. NERD is the more common manifestation of gastro-esophageal reflux disease (GERD), one of the most widespread chronic ...
- Maria Giacchino, Vincenzo Savarino, Edoardo Savarino
- Ann Gastroenterol. 2013; 26(4): 283-289.
- 2013
- 2013
Apr 29, 2010 · Currently, GERD is best treated with a PPI and provides adequate symptom relief for the majority of patients. However, targeting acid reflux does not target the cardinal mechanism underlying GER. Our current understanding is that an increased number of TLESRs is the main pathophysiological mechanism underlying GERD.
- Martin A Storr
- 10.1155/2011/626752
- 2011
- Can J Gastroenterol. 2011 Jan; 25(1): 35-38.
GORD causes symptoms such as heartburn and an unpleasant taste in the back of the mouth. It may just be an occasional nuisance for some people, but for others it can be a severe, lifelong problem. GORD can often be controlled with self-help measures and medication.
People also ask
Is nonerosive reflux disease a distinct presentation of gastroesophageal reflux disease (GERD)?
Can impedance-pH reflux patterns differentiate non-erosive reflux disease from functional heartburn?
Does microscopic esophagitis distinguish patients with non-erosive reflux disease from heartburn?
What is the difference between non-erosive reflux disease and functional heartburn?
Jan 31, 2010 · Most of the patients with GERD fall into 1 of 2 categories: nonerosive reflux disease (NERD) or erosive esophagitis. The 2 main phenotypes of GERD appear to have different pathophysiological and clinical characteristics.
