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  1. Nov 30, 2020 · The increase in opioid prescriptions in the United States has been accompanied by an increase in misuse as well as overdose and toxicity related morbidity and mortality. However, the extent of the increased opioid use, including misuse in the United Kingdom, currently remains less debated.

    • Aziza Alenezi, Asma Yahyouche, Vibhu Paudyal
    • 2021
  2. “Do No Harm” illustrates the unvarnished truth on how the medical profession and public were “duped” into creating an epidemic that could have been prevented.”

    • (7)
    • Harry Wiland, Lewis Nelson M.D., Andrew Kolodny M.D.
  3. Feb 18, 2022 · The effects of the opioid crisis have varied across diverse and socioeconomically defined urban communities, due in part to widening health disparities. The onset of the COVID-19 pandemic has coincided with a spike in drug overdose deaths in the USA.

    • Rina Ghose, Amir M. Forati, John R. Mantsch
    • J Urban Health. 2022 Apr; 99(2): 316-327.
    • 10.1007/s11524-022-00610-0
    • 2022/04
    • Chronic Opioid Therapy (COT) in The Management of CNMP
    • Trends in Prescribed Opioid Use in The UK
    • Geographical Variations and Link with Deprivation
    • The Need For Better Diagnosis and Linked Datasets
    • Role of Healthcare Professionals and The Need For Person-Centred Guidelines

    COT defined as the use of opioids on most days for more than three months, remains the mainstay of CNMP . CNMP is a condition where patients persistently or recurrently experience pain for at least three months . CNMP affects 20% of adults worldwide. In the United Kingdom (UK), studies suggest that up to half of the population (about 28 million adu...

    Many UK based studies show an upward trend in opioid prescribing and use in the National Health Services (NHS) parallel to that in the US. In 2017–2018, 12.8% of England’s population had an opioid prescription dispensed, with approximately 50% taking them for at least 1 year . A 400% rise in prescription opioids has been reported in the past decade...

    There appear to be regional variations within the UK in the prevalence of opioid use and deaths. Drug use in Scotland is disproportionately higher than in other parts of the UK. Between 2017 and 2018, Scotland had 1187 -related deaths per million populations, three times that in England and Wales . Regional variations in higher opioid-related death...

    Better use and linkage of healthcare databases are needed in the UK to obtain a clearer picture of the extent of both prescribed and illicit opioid use. There is a need to establish linked datasets to identify the magnitude of inappropriate including overprescribing, opioid abuse, diversion, adverse events including mortality, and underutilisation ...

    Person-centred care enhances the patient’s involvement in their own care to meet their unique expectations in treatment, planning, and delivery elements. Non-consideration of patient needs can lead to suboptimal outcomes. For example, in the US, the misapplication or misinterpretation of the Centre for Disease Control guideline on opioid prescribin...

    • Aziza Alenezi, Asma Yahyouche, Vibhu Paudyal
    • 2021
  4. COT is associated with various adverse efects including suicide attempts and polydrug use (opioids with alcohol or benzodiazepines) serious fractures, immunosuppression and increased risk for cardiovascular disease and early mortality.

    • Aziza Alenezi, Asma Yahyouche, Vibhu Paudyal
    • 2021
  5. Feb 25, 2020 · Based on the NPT three-part mini series, Do No Harm: The Opioid Epidemic follows author and director, Harry Wiland as he works to unearth the history and truth behind America's rampant...

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  7. Feb 25, 2020 · Do No Harm spotlights experts, journalists, and public health crusaders who are combating the special interests of Big Pharma and informing the world on how an aggressive pharmaceutical mass marketing campaign for the new drug OxyContin misled doctors and the public into our current crisis of death and addiction.

    • Harry Wiland, Lewis Nelson M.D., Andrew Kolodny M.D.
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