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  1. Speak With An Asthma Specialist & If Prescribed, Get This Asthma Treatment Delivered. Talk With A Doctor About Your Asthma Today. Convenient Delivery Options Are Available.

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  1. There are now several monoclonal antibody (mAb) therapies (“biologics”) available to treat severe asthma. Omalizumab is an anti-IgE mAb and is licensed in severe allergic asthma. Current evidence suggests it may decrease exacerbations by augmenting deficient antiviral immune responses in asthma.

    • Going to A Clinic
    • Self-Injecting at Home
    • How to Store Biologics

    You’ll usually need to attend a specialist asthma clinicto start treatment. If the clinic is not nearby, this can involve travelling so you’ll need to allow for the cost and time around that, which may include costs for childcare or time off work. You may also need to stay in the clinic for a couple of hours after your first few treatments. This is...

    You’ll need to go to the specialist clinic for your injection, but after a few weeks you may be told you can self-inject at home. 1. If you have a history of anaphylaxis your injections should always be given to you by a healthcare professional in the specialist clinic. 2. If you have no history of anaphylaxis you may be able to self-inject at home...

    If you’re using biologics yourself at home, you need to store them safely. Follow all instructions given to you by your healthcare team. You must: 1. store them in the fridge 2. keep them in their original packaging 3. keep them away from light 4. store them out of reach of children 5. use by the expiry date.

  2. May 13, 2020 · The aim of this retrospective single-center study was to evaluate the effect of biological therapy on severe asthma and to compare different therapies. We collected and analysed results of anti-IL5/IL5R and anti-IgE therapies for asthma from January 2009 until October 2019 in specialized care.

    • Emma Kotisalmi, Auli Hakulinen, Mika Mäkelä, Sanna Toppila-Salmi, Paula Kauppi
    • 2020
  3. May 24, 2023 · Severe asthma patients who experience frequent exacerbations, have poor symptom control or are OCS-dependent should be considered for further biologic therapy. 1 The six currently available biologics all successfully target eosinophilic T2 high severe asthma.

  4. Jan 12, 2022 · Biologic agents are efficacious add-on therapies for uncontrolled, severe eosinophilic asthma. These therapies represent major breakthroughs, significantly decreasing exacerbation rates and...

  5. Each biologic affects your immune system in a different way. This section explains how the six FDA-approved biologic treatments target specific immune molecules. NUCALA (mepolizumab) and CINQAIR (reslizumab) treat eosinophilic [EE-oh-sin-o-FILL-ick] asthma by targeting a molecule called interleukin-5 [enter-LOO-kin-5].

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  7. Sep 5, 2022 · Abstract. Asthma is a heterogeneous lung disease with variable phenotypes (clinical presentations) and distinctive endotypes (mechanisms). Over the last decade, considerable efforts have been made to dissect the cellular and molecular mechanisms of asthma.

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