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  1. Anthony Geary, who has portrayed Luke Spencer, was the fourth longest-running cast member, having joined General Hospital in November 1978. Geary made his last appearance on May 4, 2017. This is a list of previous cast members.

    • Jacklyn Zeman. Jacklyn Zeman was a force to be reckoned with. Entering the daytime scene 1977, Zeman was among one of the longest-lasting cast members on "General Hospital," appearing in almost 900 episodes on and off for over 42 years.
    • Sonya Eddy. Sonya Eddy, who portrayed nurse Epiphany Johnson on "General Hospital," died on December 19, 2022. Eddy joined the cast of "General Hospital" in 2006 as the brutally honest but endearing nurse.
    • Billy Miller. The devastating death of actor Billy Miller shattered the daytime television community. Miller began his admirable career on the soap opera "Young and the Restless" as the character Billy Abbott, but "General Hospital" fans fondly remember him for his portrayal of Drew Cain.
    • Tyler Christopher. Tyler Christopher was long an essential part of the "General Hospital” family. He brought the character of Nikolas Cassadine to life through heartfelt acting that tugged on viewers heartstrings.
  2. Nov 2, 2023 · In a 2012 interview, shortly before his passing, the 84-year-old noted that he portrayed his "General Hospital" character Edward Quartermaine during a period of "18 years, except the two...

    • Looper Staff
  3. General Hospital is an American television soap opera, airing on ABC. Created by Frank and Doris Hursley, the serial premiered on April 1, 1963. The longest-running cast member is Leslie Charleson, who has portrayed Monica Quartermaine since August 17, 1977, also making her one of the longest-tenured actors in American soap operas.

  4. May 3, 2024 · As previously reported, former Knots Landing and General Hospital star, Doug Sheehan has died. The actor passed away at the age of 75-years-old at his home in Wyoming with his wife, Cate Abert, by his side.

  5. May 3, 2024 · Steve Kent is set to devote his time to Sony's CBS soap The Young and the Restless. In April, news broke that Steve Kent was exiting his position as Senior Executive Vice President of Programming at Sony, where he oversaw the company's two soaps, Days of our Lives and The Young and the Restless.

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  7. John Beradino's Steve Hardy and Roy Thinnes' Phil Brewer (pictured) were two of the leading male characters in General Hospital's original cast. General Hospital was created by Frank and Doris Hursley and premiered on April 1, 1963. [1]

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