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His wife and younger children joined him in Florence, where the family was protected by the House of Medici. His sons François and Charles Louis died in Italy during these years of exile. Duke Charles himself died in Cuna in 1640. His widow and children (among them Marie, Mademoiselle de Guise) were permitted to return to France in 1643. Family
The Duke of Mayenne's nephew, the young Duke of Guise, Charles, was proposed by the Catholic League as a candidate for the throne, possibly through a marriage to Philip II of Spain's daughter Isabella, the granddaughter of Henry II of France.
Count of Guise and Duke of Guise (/ ɡ w iː z / GWEEZ, French:) were titles in the French nobility. Originally a seigneurie, in 1417 Guise was erected into a county for René, a younger son of Louis II of Anjou.
Charles de Lorraine, 4th Duke of Guise born 2nd August 1571 at Joinville in the Haute- Marne Department in the Champagne-Ardenne North West region of France, was the son of Henry I, Duke of Guise and Catherine of Cleves and one of fourteen children.
His wife and younger children joined him in Florence, where the family was protected by the House of Medici. His sons François and Charles Louis died in Italy during these years of exile. Duke Charles himself died in Cuna in 1640. His widow and children (among them Marie, Mademoiselle de Guise) were permitted to return to France in 1643. Family []
Claude de Lorraine (1496–1550) was created the 1st duke de Guise in 1527 for his service to Francis I in the defense of France. Claude’s sons François, 2nd duke de Guise, and Charles, cardinal de Lorraine (1524–1574), gained great power during the reign of Francis II.
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Charles de Lorraine, 4th Duke of Guise and 3rd Prince of Joinville, was the son of Henry I, Duke of Guise and Catherine of Cleves, and succeeded his father as Duke of Guise in 1588. Initially part of the Catholic league, he pledged his support for Henry IV of France and was made Admiral of the Levant by Louis XIII of France.
