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  1. Jul 8, 2024 · Physician scientist Brian Feldman and molecular biologist Liang Li from the University of California, San Francisco carried out a number of experiments on human cell cultures and mice engineered with a switch for a gene they hypothesized regulates the maintenance of our fat.

  2. 6 days ago · The pathway could be a potential target for weight loss drugs, said lead researcher Brian Feldman, MD, PhD, a professor of pediatrics at UCSF.

  3. Jul 1, 2024 · Address correspondence to: Brian J. Feldman, Department of Pediatrics, University of California, San Francisco School of Medicine, San Francisco, California 94158, USA. Phone: 415.514.0610; Email: Brian.Feldman@ucsf.edu. Find articles by Li, L. in: JCI | PubMed | Google Scholar.

  4. Jul 1, 2024 · Brian Feldman, MD. Humans and many other mammals are born with brown fat deposits that help them maintain body temperature after birth. But, while a human baby’s brown fat disappears in the first year of life, beige fat persists. Humans can naturally turn white fat cells into beige ones in response to diet or a cold environment.

  5. Jul 2, 2024 · “A lot of people thought this wasn’t feasible,” said Brian Feldman, MD, PhD, the Walter L. Miller, MD Distinguished Professor in Pediatric Endocrinology and senior author of the study.

  6. Jul 3, 2024 · We showed not only that this approach works to turn these white fat cells into beige ones, but also that the bar to doing so isn't as high as we'd thought," said Brian Feldman, professor in ...

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  8. Jul 1, 2024 · Abstract. Healthy adipose tissue is essential for normal physiology. There are 2 broad types of adipose tissue depots: brown adipose tissue (BAT), which contains adipocytes poised to burn energy through thermogenesis, and white adipose tissue (WAT), which contains adipocytes that store lipids.

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