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What causes Huntington's disease?
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What is Huntington's disease (HD)?
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Can Huntington's disease cause movement disorders?
Huntington's disease is caused by a faulty gene that results in parts of the brain becoming gradually damaged over time. You're usually only at risk of developing it if one of your parents has or had it.
- Symptoms
Huntington's disease can cause a wide range of symptoms,...
- Treatment and Support
There's currently no cure for Huntington's disease or any...
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The Huntington's Disease Association has more information...
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This build-up causes nerve cells to function less well and...
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Huntington's disease causes nerve cells in the brain to decay over time. The disease affects a person's movements, thinking ability and mental health. Huntington's disease is rare. It's often passed down through a changed gene from a parent. Huntington's disease symptoms can develop at any time, but they often begin when people are in their 30s or ...
Huntington's disease usually causes movement disorders. It also causes mental health conditions and trouble with thinking and planning. These conditions can cause a wide spectrum of symptoms. The first symptoms vary greatly from person to person. Some symptoms appear to be worse or have a greater effect on functional ability. These symptoms may cha...
Huntington's disease is caused by a difference in a single gene that's passed down from a parent. Huntington's disease follows an autosomal dominant inheritance pattern. This means that a person needs only one copy of the nontypical gene to develop the disorder. With the exception of genes on the sex chromosomes, a person inherits two copies of eve...
People who have a parent with Huntington's disease are at risk of having the disease themselves. Children of a parent with Huntington's have a 50 percent chance of having the gene change that causes Huntington's.
After Huntington's disease starts, a person's ability to function gradually gets worse over time. How quickly the disease gets worse and how long it takes varies. The time from the first symptoms to death is often about 10 to 30 years. Juvenile Huntington's disease usually results in death within 10 to 15 years after symptoms develop. The depressio...
People with a known family history of Huntington's disease may be concerned about whether they may pass the Huntington gene on to their children. They might consider genetic testing and family planning options. If an at-risk parent is considering genetic testing, it can be helpful to meet with a genetic counselor. A genetic counselor explains the p...
Jul 19, 2024 · Huntington’s disease (HD) is an inherited disorder that causes nerve cells (neurons) in parts of the brain to gradually break down and die. The disease attacks areas of the brain that help to control voluntary (intentional) movement, as well as other areas.
Oct 7, 2024 · Huntington’s disease is a condition that damages nerve cells in the brain causing them to stop working properly. It’s passed on (inherited) from a person’s parents. The damage to the brain gets worse over time. It can affect movement, cognition (perception, awareness, thinking, judgement) and mental health.
About 99% of HD diagnoses based on the typical symptoms and a family history of the disease are confirmed by genetic testing to have the expanded trinucleotide repeat that causes HD. Most of the remaining are called HD-like (HDL) syndromes .
Dec 20, 2023 · Huntington's disease is a genetically inherited condition that causes parts of the brain and nervous system to stop working properly over time. It is a slowly progressive condition that interferes with the movements of your body, thinking and judgement, and can lead to a change in your behaviour.
Aug 23, 2023 · Huntington disease is an autosomal dominant disorder caused by the elongation of CAG repeats on the short arm of chromosome 4p16.3 in the HTT gene. The gene encodes for the HTT protein, which plays a role in the synaptic function and also plays a crucial role in the post-embryonic period.
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