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  1. In 1804, the United States acquired St. Louis as part of the Louisiana Purchase. In the 19th century, St. Louis developed as a major port on the Mississippi River; from 1870 until the 1920 census, it was the fourth-largest city in the country.

  2. 1 day ago · St. Louis, city, adjacent to but independent of St. Louis county, east-central Missouri, U.S. It lies on the west bank of the Mississippi River (bridged there at several points) opposite East St. Louis, Illinois, just south of the confluence of the Missouri River.

  3. St. Louis. The Gateway City of St. Louis is the epitome of the modern Midwestern metropolis. Missouri's second-largest city is vibrant but laid-back, populous but navigable, historic but still relevant. Map.

  4. Find inspiration for your next trip to St. Louis, from local favorites to world-renowned attractions. With our visitors guide, you can discover the best hotels, restaurants, attractions, events and other entertainment options in the Gateway City.

  5. St. Louis, one of the oldest cities in Missouri, began when a man named Pierre Laclede Liguest discovered the perfect place for a trading post on a high bluff of the Mississippi River in 1763.

  6. Slide into St Louis and revel in the unique vibe of the largest city in the Great Plains. Beer, bowling and baseball are some of the top attractions, but history and culture, much of it linked to the Mississippi River, are a vital part of the fabric.

  7. The Gateway City of St. Louis is the epitome of the modern Midwestern metropolis. Missouri's second-largest city is vibrant but laid-back, populous but navigable, historic but still relevant. The city's planners have created an aesthetically beautiful city, with plenty of green space amidst buildings both old and new, framed by the majestic ...

  8. St. Louis is a large and major city in the U.S. state of Missouri. It is by the Mississippi River. It was founded by the French. It was named after King Louis IX of France, who is also a Saint. It is often called the "Gateway City" because it was important to settlers traveling out west. Its most famous landmark is the Gateway Arch.

  9. St. Louis has welcomed visitors from far and wide since the city hosted the World’s Fair in 1904. Today, the Gateway City is filled with myriad museums, natural attractions, historical sites...

  10. Marked by the Gateway Arch, St. Louis is home to a thriving brewery scene, several exciting restaurants, and loads of free activies, from the 90-acre Saint Louis Zoo to world-class museums to the sprawling lawns of Forest Park.

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