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1. www.health.harvard.edu › pain › whichWhich antidepressants are best for treating chronic pain?

   www.health.harvard.edu › pain › which

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   May 1, 2023 · Antidepressants are used to treat chronic pain even in people who do not have depression. A 2023 study found that serotonin-norepinephrine reuptake inhibitors were the most effective and treated the largest number of pain conditions.

   • Email: hhp_info@health.harvard.edu

2. bnf.nice.org.uk › treatment-summaries › pain-chronicPain, chronic | Treatment summaries | BNF | NICE

   bnf.nice.org.uk › treatment-summaries › pain-chronic

   For guidance on the management of pain in specific conditions, see Diverticular disease and diverticulitis, Endometriosis, Irritable bowel syndrome, Low back pain and sciatica, Migraine, Neuropathic pain, Osteoarthritis, Rheumatoid arthritis, Spondyloarthritis, and Ulcerative colitis.

3. www.mayoclinic.org › pain-medications › art-20045647Antidepressants: Another weapon against chronic pain - Mayo ...

   www.mayoclinic.org › pain-medications › art-20045647

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   People with chronic pain often develop depression along with their chronic pain. Venlafaxine and duloxetine offer the advantage of being effective for depression and anxiety at the same dosages useful for treating pain.

4. www.nhs.uk › mental-health › talking-therapiesOverview - Antidepressants - NHS

   www.nhs.uk › mental-health › talking-therapies

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   • Selective Serotonin Reuptake Inhibitors
   • Serotonin-noradrenaline Reuptake Inhibitors
   • Noradrenaline and Specific Serotonergic Antidepressants
   • Tricyclic Antidepressants
   • Serotonin Antagonists and Reuptake Inhibitors
   • Monoamine Oxidase Inhibitors

   SSRIs are the most widely prescribed type of antidepressants. They're usually preferred over other antidepressants, as they cause fewer side effects. An overdose is also less likely to be serious. Fluoxetine is probably the best known SSRI (sold under the brand name Prozac). Other SSRIs include citalopram (Cipramil), escitalopram (Cipralex), paroxe...

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   SNRIs are similar to SSRIs. They were designed to be a more effective antidepressant than SSRIs. However, the evidence that SNRIs are more effective in treating depression is uncertain. It seems that some people respond better to SSRIs, while others respond better to SNRIs. Examples of SNRIs include duloxetine (Cymbalta and Yentreve) and venlafaxin...

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   NASSAs may be effective for some people who are unable to take SSRIs. The side effects of NASSAs are similar to those of SSRIs, but they're thought to cause fewer sexual problems. However, they may also cause more drowsiness at first. The main NASSA prescribed in the UK is mirtazapine(Zispin).

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   TCAs are an older type of antidepressant. They're no longer usually recommended as the first treatment for depression because they can be more dangerous if an overdose is taken. They also cause more unpleasant side effects than SSRIs and SNRIs. Exceptions are sometimes made for people with severe depression that fail to respond to other treatments....

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   SARIs are not usually the first choice of antidepressant, but they may be prescribed if other antidepressants have not worked or have caused side effects. The main SARI prescribed in the UK is trazodone(Molipaxin).

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   MAOIs are an older type of antidepressant that are rarely used nowadays. They can cause potentially serious side effects so should only be prescribed by a specialist doctor. Examples of MAOIs include tranylcypromine, phenelzine and isocarboxazid.

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5. www.webmd.com › chronic-pain-depressionChronic Pain and Depression Treatment: Antidepressants and ...

   www.webmd.com › chronic-pain-depression

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   May 13, 2023 · In addition to being a primary treatment for depression, some antidepressants are effective in the treatment of many chronic pain syndromes, such as nerve-related pain disorders (for example,...

6. www.mayoclinic.org › diseases-conditionsHelpful for chronic pain in addition to depression

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   Oct 5, 2019 · Serotonin and norepinephrine reuptake inhibitors (SNRIs) are a class of medications that are effective in treating depression. SNRIs are also sometimes used to treat other conditions, such as anxiety disorders and long-term (chronic) pain, especially nerve pain.

7. People also ask

   What drugs are used to relieve chronic pain?

   • These drugs may also be used to help relieve chronic pain: Serotonin and norepinephrine reuptake inhibitors (SNRIs). Some SNRIs, such as venlafaxine (Effexor XR), duloxetine (Cymbalta, Drizalma Sprinkle), milnacipran (Savella) and desvenlafaxine (Pristiq), may help relieve chronic pain.

   Antidepressants: Another weapon against chronic pain

   www.mayoclinic.org/pain-medications/art-20045647

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   Can antidepressants treat chronic pain?

   • Antidepressants are used to treat chronic pain even in people who do not have depression. A 2023 study found that serotonin-norepinephrine reuptake inhibitors were the most effective and treated the largest number of pain conditions.

   Which antidepressants are best for treating chronic pain?

   www.health.harvard.edu/pain/which-antidepressants-are-best-for-treating-chronic-pain

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   What are the treatment options for chronic pain?

   • Treatment aims to reduce pain and the impact of chronic pain on quality of life, mood, and function. A wide range of both pharmacological and non-pharmacological management strategies are available for chronic pain. Where possible, treatment options should be guided by any known underlying chronic pain condition (s).

   Pain, chronic | Treatment summaries | BNF | NICE

   bnf.nice.org.uk/treatment-summaries/pain-chronic/

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   Which SNRIs help relieve chronic pain?

   • Serotonin and norepinephrine reuptake inhibitors (SNRIs). Some SNRIs, such as venlafaxine (Effexor XR), duloxetine (Cymbalta, Drizalma Sprinkle), milnacipran (Savella) and desvenlafaxine (Pristiq), may help relieve chronic pain. People with chronic pain often develop depression along with their chronic pain.

   Antidepressants: Another weapon against chronic pain

   www.mayoclinic.org/pain-medications/art-20045647

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   What types of analgesics are used in the treatment of chronic pain?

   • A variety of analgesics are used in the treatment of chronic pain and can be divided into non-opioid, opioid, and adjuvant analgesics. Individual responses to analgesia vary considerably, both in terms of efficacy and side-effects; even with the same chronic pain syndrome, the underlying pain mechanisms may differ between individuals.

   Pain, chronic | Treatment summaries | BNF | NICE

   bnf.nice.org.uk/treatment-summaries/pain-chronic/

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   Does milnacipran relieve fibromyalgia pain?

   • Milnacipran is used to relieve fibromyalgia pain and can cause side effects such as nausea and drowsiness. However, it has shown only limited effectiveness in relieving other types of pain. Selective serotonin reuptake inhibitors (SSRIs).

   Antidepressants: Another weapon against chronic pain

   www.mayoclinic.org/pain-medications/art-20045647

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8. www.webmd.com › depression › depression-chronic-painDepression and Chronic Pain: Causes and Treatments - WebMD

   www.webmd.com › depression › depression-chronic-pain

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   Sep 13, 2023 · Depression magnifies pain. It makes everyday living more difficult. Still, it's important to know that medications and psychotherapy can help relieve the depression and make chronic pain more...