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- Atypical cells are cells that are suspicious of malignancy and may support the early detection or surveillance of bladder cancer.
www.sysmex-europe.com/academy/knowledge-centre/sysmex-parameters/atypical-cells/
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Can urine cytology detect atypical urothelial cells?
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Nov 1, 2009 · The “atypical urothelial cell” cytologic category is nonstandardized. We subclassify atypical cases to “atypical, favor a reactive process” or “atypical, unclear if reactive or neoplastic.” We evaluated the predictive significance of atypical cases by looking at their histologic follow-up.
- Fadi Brimo, Robin T. Vollmer, Bruce Case, Armen Aprikian, Wassim Kassouf, Manon Auger
- 2009
May 5, 2022 · Urinary cytology is most helpful in diagnosing invasive high-grade (the cancer cells grow and spread quickly) tumors and carcinoma in situ (a group of abnormal cells that are found only in the place where they first formed in the body).
Nov 17, 2009 · Increased cellularity, papillary cell clusters, nuclear membrane irregularity, hyperchromasia and India-ink type nuclei were observed more frequently in the atypical malignant urine samples, while cytoplasmic vacuolization were seen more in the negative reactive urine samples.
- Ghadeer A Mokhtar, Mohamed Al-Dousari, Doaa Al-Ghamedi
- 10.4103/0974-7796.68857
- 2010
- Urol Ann. 2010 Sep-Dec; 2(3): 100-106.
Atypical cells are cells with a suspicion of malignancy. Among others, these cells show increased N:C ratio and irregular chromatin patterns.
Mar 27, 2013 · Overall, 271 of 1320 initial atypical urine specimens (21%) progressed to positive cytology or surgical pathology results with a mean time to progression of 155 days. Of the cases that progressed to malignancy, 118 were high-grade urothelial carcinoma and 92 were low-grade urothelial carcinoma.
- Julianne Muus Ubago, Vikas Mehta, Eva M. Wojcik, Güliz A. Barkan
- 68
- 2013
- 27 March 2013
Feb 3, 2022 · According to The Paris System for reporting urinary cytology, the “atypical urothelial cells” category is associated with a 24–53% risk of high-grade malignancy. Follow-up is recommended as clinically warranted.
Apr 13, 2024 · In the limited available literature, atypical squamous cells (ASC) are a rare finding, with a reported incidence of 0.3%–0.9% of urine specimens. 1, 2 Their presence has been associated with various conditions, including reactive changes, inflammation, infection, and neoplasms.
