Search results
- Ensuring that robust and reliable data are available to researchers within and outside the federal government is critical to 1) understanding and tracking the crisis, 2) informing treatment and prevention efforts, and 3) reducing opioid-related morbidity and mortality.
www.ncbi.nlm.nih.gov/books/NBK605137/
Jun 24, 2022 · Here, we present a model-based analysis of 11 strategies related to opioid misuse and OUD prevention, buprenorphine capacity, recovery support, and overdose harm reduction and their impacts on OUD prevalence and fatal opioid overdoses.
- 10.1126/sciadv.abm8147
- 2022/06
- Sci Adv. 2022 Jun; 8(25): eabm8147.
Optimal public health efforts to reduce the number of deaths from opioid overdoses require approaching the problem from a range of angles, including prevention, treatment, and harm reduction. Considering the role of the vector in the opioid crisis is also important.
- Wilson M. Compton, Christopher M. Jones
- 10.1111/nyas.14209
- 2019
- 2019/09
Apr 5, 2024 · The number of opioid-related deaths has been rising continuously since 1999. Three distinct waves of increases are related to different types of opioids throughout the last 25 years. Increasing communities' support, capacity, and education may help turn the tide and prevent overdose deaths.
- Key Facts
- Opioids
- Opioid Overdose
- Risk Factors For Opioid Overdose
- Emergency Responses to Opioid Overdose
- People Most Likely to Witness An Opioid Overdose
- Prevention of Opioid Overdose
- Who Response and Recommendations
The term “opioids” includes compounds that are extracted from the poppy plant (Papaver somniferum)as well as semisynthetic and synthetic compounds with similar properties that can interact with opi...Opioids are commonly used for the treatment of pain, and include medicines such as morphine, fentanyl and tramadol.Their non-medical use, prolonged use, misuse and use without medical supervision can lead to opioid dependence and other health problems.Due to their pharmacological effects, opioids can cause breathing difficulties, and opioid overdose can lead to death.The term “opioids” includes compounds that are extracted from the poppy plant (Papaver somniferum) as well as semisynthetic and synthetic compounds with similar properties that can interact with opioid receptors in the brain. Opioids have analgesic and sedative effects, and such medicines as morphine, codeine and fentanyl are commonly used for the ...
Opioid use can lead to death due to the effects of opioids on the part of the brain which regulates breathing. An opioid overdose can be identified by a combination of three signs and symptoms: 1. pinpoint pupils 2. unconsciousness 3. difficulties with breathing. Worldwide, about 600 000 deaths were attributable to drug use in 2019. Close to 80% of...
There are a number of risk factors for opioid overdose. These include: 1. having an opioid use disorder; 2. taking opioids by injection; 3. resumption of opioid use after an extended period of abstinence (e.g. following detoxification, release from incarceration, cessation of treatment); 4. using prescription opioids without medical supervision; 5....
Death following opioid overdose is preventable if the person receives basic life support and the timely administration of the drug naloxone. Naloxone is an antidote to opioids that will reverse the effects of an opioid overdose if administered in time. Naloxone has virtually no effect in people who have not taken opioids. Access to naloxone is gene...
People who are most likely to witness an opioid overdose are: 1. people at risk of an opioid overdose themselves; 2. friends and families of people who use opioids on a regular basis; and 3. health-care workers, the emergency services, people providing accommodation to people who use opioids, and peer education and outreach workers as well as other...
Beyond approaches to reducing drug use in general in the community, there are specific measures to prevent opioid overdose. These include: 1. increasing the availability of opioid dependence treatment, including for those dependent on prescription opioids; 2. reducing and preventing irrational or inappropriate opioid prescribing; 3. monitoring opio...
WHO supports countries in their efforts to ensure rational use of opioids and their optimal availability for medical purposes and minimization of their misuse and non-medical use. Following the recommendation of WHO’s Expert Committee on Drug Dependence (6), a number of synthetic opioids, including fentanyl analogues, have been placed under interna...
Nov 14, 2018 · Epidemiological and clinical data provide context for understanding the range of adverse outcomes directly related to fatal opioid overdose, opioid use and misuse, and opioid use disorder; the medical and social consequences that are driven by opioid misuse; and programs and policies that may either contribute to or mitigate negative outcomes ...
- Brendan Saloner, Emma E. McGinty, Leo Beletsky, Ricky Bluthenthal, Chris Beyrer, Michael Botticelli,...
- 10.1177/0033354918793627
- 2018
- Nov-Dec 2018
Apr 3, 2024 · Evidence-based interventions intended to reduce risk of fatal opioid overdose, such as through harm reduction efforts (eg, naloxone), were estimated to decrease fatal opioid overdoses by up to 37% (scenarios B and D).
Jul 9, 2024 · These results suggest that robust, multi-faceted measures are even more important in light of the COVID-19 pandemic to prevent overdoses and educate users on the risks associated with potent synthetic opioids such as fentanyl.
