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  2. Minimum Inhibitory Concentration (MIC) is the lowest concentration (expressed as mg/L or μg/μL) of an antimicrobial agent that inhibits the visible in-vitro growth of microorganisms. The MIC test determines the antimicrobial activity of a test agent against a specific bacteria.

    • 5 min
  3. Dec 29, 2021 · A positive correlation was found between MIC and MBC values for most of the biocides and antibiotics. The higher the hydrophobicity of the cell surface, the higher the susceptibility to biocides, suggesting that surface characteristics of bacterial cells influence resistance to these compounds.

    • 10.3390/biology11010046
    • 2022/01
    • Biology (Basel). 2022 Jan; 11(1): 46.
  4. May 20, 2024 · Understanding the differences between Minimum Bactericidal Concentration (MBC) and Minimum Inhibitory Concentration (MIC) is very important for anyone involved in the development of antimicrobial drugs.

  5. Jun 26, 2023 · The main difference between MIC and MBC is that MIC is the minimum inhibitory concentration or the lowest concentration of antimicrobial drug that will inhibit the visible growth of bacteria after overnight incubation, whereas MBC is the minimal bactericidal concentration or the lowest concentration of antibacterial agent required to kill a ...

  6. Feb 4, 2021 · Minimal inhibitory concentration (MIC) defines in vitro levels of susceptibility or resistance of specific bacterial strains to applied antibiotic. Reliable assessment of MIC has a significant impact on the choice of a therapeutic strategy, which affects efficiency of an infection therapy.

    • Beata Kowalska-Krochmal, Ruth Dudek-Wicher
    • 10.3390/pathogens10020165
    • 2021
    • Pathogens. 2021 Feb; 10(2): 165.
  7. The minimum bactericidal concentration (MBC) is the lowest concentration of an antibacterial agent required to kill a particular bacterium. It can be determined from broth dilution minimum inhibitory concentration (MIC) tests by subculturing to agar plates that do not contain the test agent.

  8. The MIC is the lowest concentration of antibiotic that prevents visible growth of the organism. Antibiotics are typically considered to be bacteriostatic if the ratio of the MBC to the MIC is greater than 4. However, technical aspects of testing can have a significant impact on the results.

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