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  1. Congenital Hypothyroidism. Hypothyroidism is a condition that results from an under-active thyroid that does not produce enough thyroid hormone. ‘Congenital’ means that this condition is present at birth. Very early in an unborn baby's development the thyroid gland moves from the back of the tongue to its normal position in the neck.

    • 1.1 Information for people with thyroid disease, their families and carers. Presenting information. 1.1.1 Ensure that information is presented to facilitate shared decision making, as recommended in the NICE guideline on shared decision making.
    • 1.2 Investigating suspected thyroid dysfunction. Indications for tests for thyroid dysfunction. 1.2.1 Consider tests for thyroid dysfunction for adults, children and young people if there is a clinical suspicion of thyroid disease, but bear in mind that 1 symptom alone may not be indicative of thyroid disease.
    • 1.3 Managing primary hypothyroidism. Tests for people with confirmed primary hypothyroidism. Adults. 1.3.1 Consider measuring thyroid peroxidase antibodies (TPOAbs) for adults with TSH levels above the reference range, but do not repeat TPOAbs testing.
    • 1.4 Follow-up and monitoring of primary hypothyroidism. Tests for follow-up and monitoring of primary hypothyroidism. 1.4.1 Aim to maintain TSH levels within the reference range when treating primary hypothyroidism with levothyroxine.
  2. Jun 30, 2021 · Treatment with L–T4 should be advised for children using medications, such as antiepileptic medications and IFN α, with a TSH level >10 mIU/L until drugs are stopped [30,31]. Last, children with persistent SH and diffuse or nodular goiter should be treated with L–T4 replacement with the aim of normalizing serum TSH levels to protect against the development of thyroid carcinomas [ 50 ].

    • Kotb Abbass Metwalley, Hekma Saad Farghaly
    • 2021
  3. When considering whether to start treatment for subclinical hypothyroidism, take into account features suggesting underlying thyroid disease. A Strength of recommendation: High. In children aged 28 days to under 2 years, consider levothyroxine sodium for those who have a TSH level of 10 mIU/L or higher. A Strength of recommendation: High

  4. Mar 1, 2013 · Abstract. Graves’ disease (GD) is the most common cause of hyperthyroidism in children. This review gives an overview and update of management of GD. Antithyroid drugs (ATD) are recommended as the initial treatment, but the major problem is the high relapse rate (30%) as remission is achieved after a first course of ATD.

  5. people who have thyroid disease or don’t have a thyroid gland (typically, someone who doesn’t have a thyroid gland will have had surgery to remove the gland. Very rarely, a person will be born without a thyroid gland). In general, when thyroid hormone treatment is needed, just the T4 form is prescribed. This medication comes in pill

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