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Communication between cells, both through cell–cell contact and via the ECM and diffusible factors, and using both chemical and mechanical signals, is at the heart of polarized tissue and organ formation.
- David M. Bryant, Keith E. Mostov
- 10.1038/nrm2523
- 2008
- 2008/11
Apr 1, 2017 · Cell polarity can develop de novo, be maintained through rounds of cell division and be dynamically remodeled. In this Cell Science at a Glance review and poster, we describe molecular asymmetries that underlie cell polarity in several cellular contexts.
- Joseph P. Campanale, Thomas Y. Sun, Denise J. Montell
- 2017
The male centrosome provides a cue, which breaks an initially homogenous membrane distribution of anterior PARs by inducing cortical flows. These are thought to advect anterior PARs towards one side of the cell, allowing posterior PARs to bind to other pole (posterior).
Aug 1, 2014 · Cell polarity is characterised by differences in structure, composition and function between at least two poles of a cell. In epithelial cells, these spatial differences allow for the formation of defined apical and basal membranes.
- Jessica L. Lee, Charles H. Streuli
- 2014
Nov 1, 2008 · Key Points. Most cells in the body are polarized, showing some level of shape and functional asymmetry, such as apico–basal or front–back polarity. Tissues are formed from the coordinated...
- David M. Bryant, Keith E. Mostov
- 2008
Sep 15, 2012 · The PIN auxin-efflux carriers represent molecular landmarks of cell polarity because they usually are localized to one side of the cell, thus driving the polar flux of auxin in tissues .
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Mar 10, 2009 · In eukaryotic cells microtubules and actin filaments help to generate the spatial organization of the cytoplasm that is required for polarity and shape. Recent work in fission yeast demonstrates that changing cell shape in turn reorganizes the cytoskeleton and cell polarization machinery.