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  1. A psychiatrist hires his mistress to help him kill his wife, but Lt. Columbo suspects him and investigates. IMDb provides cast and crew information, user and critic reviews, trivia, goofs, quotes, and more for this crime drama mystery.

    • (5.6K)
    • Crime, Drama, Mystery
    • Richard Irving
    • 1968-02-20
  2. Aug 19, 2015 · Take Prescription: Murder for what it is and you have a brilliantly crafted mystery, a supremely suave baddie, and a smart lawman who gets inside the head of his quarry and beats him at his own game – all vital ingredients for the success story the show would become. Who can complain about that?

    • 11 min
  3. Prescription: Murder (TV Movie 1968) cast and crew credits, including actors, actresses, directors, writers and more.

  4. Prescription: Murder is the first ever episode of Columbo. It first aired on February 20, 1968 and was directed by Richard Irving. The episode stars Peter Falk in his first appearance as Lieutenant Columbo and Gene Barry as the series' first murderer, Dr. Ray Fleming.

  5. A psychiatrist hires his mistress to help him kill his wealthy wife and stage it as a robbery, but Lt. Columbo suspects him and investigates. The web page provides a detailed synopsis of the story, cast and crew, user reviews, trivia and more.

  6. Watch the first episode of the classic crime drama series Columbo, starring Peter Falk as the clever detective who outwits a murderous psychiatrist. Prescription: Murder is a mystery about a wife's death that looks like a robbery gone wrong.

  7. “Prescription: Murder” (1968) PLOT: An arrogant, nonchalant psychiatrist (Gene Barry) murders his wife and uses his naïve actress girlfriend to get away with it (Katherine Justice), but Lt. Columbo strongly suspects the therapist and steadfastly works to obtain evidence.

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