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  1. A randomized controlled trial (or randomized control trial; RCT) is a form of scientific experiment used to control factors not under direct experimental control.

  2. Randomized controlled trials (RCT) are prospective studies that measure the effectiveness of a new intervention or treatment. Although no study is likely on its own to prove causality, randomization reduces bias and provides a rigorous tool to examine cause-effect relationships between an intervention and outcome.

    • Eduardo Hariton, Joseph J Locascio
    • 2018
  3. Jan 17, 1998 · Randomised controlled trials are the most rigorous way of determining whether a cause-effect relation exists between treatment and outcome and for assessing the cost effectiveness of a treatment. They have several important features: Random allocation to intervention groups.

    • Bonnie Sibbald, Martin Roland
    • 1998
  4. A randomized controlled trial is a prospective, comparative, quantitative study/experiment performed under controlled conditions with random allocation of interventions to comparison groups.

    • Amar Bhide, Prakesh S. Shah, Prakesh S. Shah, Ganesh Acharya, Ganesh Acharya
    • 2018
  5. Randomized controlled trials (RCTs) are considered the highest level of evidence to establish causal associations in clinical research. There are many RCT designs and features that can be selected to address a research hypothesis.

    • Emily C. Zabor, Alexander M. Kaizer, Brian P. Hobbs
    • 2020
  6. A randomized controlled trial (RCT) is a prospective experimental design that randomly assigns participants to an experimental or control group. RCTs are the gold standard for establishing causal relationships and ruling out confounding variables and selection bias.

  7. Jul 2, 2020 · Randomized controlled trials (RCTs) are considered the highest level of evidence to establish causal associations in clinical research. There are many RCT designs and features that can be selected to address a research hypothesis.

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