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The minimum bactericidal concentration (MBC) is the lowest concentration of an antibacterial agent required to kill a particular bacterium. It can be determined from broth dilution minimum inhibitory concentration (MIC) tests by subculturing to agar plates that do not contain the test agent.
The MBC is determined by performing serial dilutions of an antibiotic to determine the lowest concentration that results in a ≥99.9% reduction of the original organism inoculum upon subculture to an antibiotic-free medium.
Minimum bactericidal concentration (MBC): The lowest concentration of antibiotic that kills a specified proportion of the starting population within a fixed timeframe. For example, the MBC 99 is the concentration of antibiotic that kills 99% of the starting population at a predetermined time point.
May 25, 2024 · The MBC test determines the lowest concentration at which an antimicrobial agent will kill a particular microorganism. The MBC is determined using a series of steps, undertaken after a Minimum Inhibitory Concentration (MIC) test has been completed.
Also termed minimum lethal concentration (MLC), the MBC of an antibacterial agent is determined by subculturing the last clear MIC tube onto the growth medium and examining for bacterial growth. Normally, for bactericidal drugs, the MIC is very close or just one step from the MBC.
Minimum bactericidal concentration (MBC) value was determined the minimum concentration of the drug to kill 99.9% of bacteria. MBC was also used to evaluate the bactericidal ability of ruthenium complexes.
May 9, 2023 · The minimum bactericidal concentration (MBC) test can be used to assess the ability of an antimicrobial agent to kill a bacterial isolate. MBC tests are performed after consultation in very specific clinical situations when it is necessary to determine….
